Drug-drug interactions between propofol and ART drugs: inhibiting neuronal activity by affecting glucose metabolism
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چکیده
منابع مشابه
Investigating the Factors Affecting Drug-drug Interactions
A drug-drug interaction (DDI) is a change in the effect of a drug when administered with another drug or group of drugs. Drug interactions are common and cause increased hospital admission rates, treatment failure, avoidable medical complications, and even deaths. A literature survey is conducted to find factors affecting drug-drug interactions in cohorts that are more likely to be affected by ...
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The consensus of current international guidelines for the treatment of HIV infection is that data on therapeutic drug monitoring (TDM) of non-nucleoside reverse transcriptase inhibitors (NNRTIs) and protease inhibitors (Pls) provide a framework for the implementation of TDM in certain defined scenarios in clinical practice. However, the utility of TDM is considered to be on an individual basis ...
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Orally delivered small-molecule therapeutics are metabolized in the liver and intestine by phase I and phase II drug-metabolizing enzymes (DMEs), and transport proteins coordinate drug influx (phase 0) and drug/drug-metabolite efflux (phase III). Genes involved in drug metabolism and disposition are induced by xenobiotic-activated nuclear receptors (NRs), i.e. PXR (pregnane X receptor) and CAR ...
متن کاملInteractions between drugs and sulforaphane modulate the drug metabolism enzymatic system.
BACKGROUND Sulforaphane (SFN) is a potent chemopreventive agent, which is widely consumed in diet or as a diet supplement. It modulates the enzymes of II and III metabolism phase. In this paper, the influence of SFN and three commonly consumed drugs: furosemide, verapamil and ketoprofen on II and III metabolisms phase enzymes was studied. We have also investigated if the interactions between SF...
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ژورنال
عنوان ژورنال: Annals of Translational Medicine
سال: 2023
ISSN: ['2305-5839', '2305-5847']
DOI: https://doi.org/10.21037/atm-23-255